The EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation

The EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes hemorrhagic colitis and may result in potentially fatal hemolytic uremia syndrome in humans. EHEC colonize the intestinal mucosa and promote the formation of actin-rich pedestals via translocated type III effectors. Two EHEC type III secreted...

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Bibliographic Details
Main Authors: Piscatelli, Heather (Author), Kotkar, Shalaka A. (Author), McBee, Megan E. (Contributor), Muthupalani, Sureshkumar (Contributor), Schauer, David B. (Contributor), Mandrell, Robert E. (Author), Leong, John M. (Author), Zhou, Daoguo (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2011-08-26T15:12:26Z.
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