Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

RNA interference (RNAi) is a cellular process whereby the silencing of a particular gene is mediated by short RNAs (siRNAs). Although siRNAs have great therapeutic potential, cellular delivery has been a challenge. Nanoparticle-siRNA conjugates have emerged as potential delivery vehicles; however, r...

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Bibliographic Details
Main Authors: Singh, Neetu (Contributor), Agrawal, Amit (Contributor), Leung, Anthony (Contributor), Sharp, Phillip A. (Contributor), Bhatia, Sangeeta N. (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2011-08-31T17:49:28Z.
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