Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference
RNA interference (RNAi) is a cellular process whereby the silencing of a particular gene is mediated by short RNAs (siRNAs). Although siRNAs have great therapeutic potential, cellular delivery has been a challenge. Nanoparticle-siRNA conjugates have emerged as potential delivery vehicles; however, r...
Main Authors: | Singh, Neetu (Contributor), Agrawal, Amit (Contributor), Leung, Anthony (Contributor), Sharp, Phillip A. (Contributor), Bhatia, Sangeeta N. (Contributor) |
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Other Authors: | Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society,
2011-08-31T17:49:28Z.
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Subjects: | |
Online Access: | Get fulltext |
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