Quantifying the nanomachinery of the nanoparticle-biomolecule interface

Quantifying the nanomachinery of the nanoparticle-biomolecule interface

A study is presented of the nanomechanical phenomena experienced by nanoparticle-conjugated biomolecules. A thermodynamic framework is developed to describe the binding of thrombin-binding aptamer (TBA) to thrombin when the TBA is conjugated to nanorods. Binding results in nanorod aggregation (viz....

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Bibliographic Details
Main Authors: de Puig Guixe, Helena (Contributor), Federici, Stefania (Contributor), Baxamusa, Salmaan H. (Contributor), Bergese, Paolo (Contributor), Hamad-Schifferli, Kimberly (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Wiley-VCH, 2011-09-12T21:28:09Z.
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