The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation

The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation

Lrs4 and Csm1, components of the monopolin complex, localize to the rDNA where they regulate rDNA maintenance and segregation. During meiosis, the complex also associates with kinetochores to bring about sister kinetochore co-orientation, an essential aspect of meiosis I chromosome segregation. We s...

Full description

Bibliographic Details
Main Authors: Brito, Ilana Lauren (Contributor), Monje-Casas, Fernando (Author), Amon, Angelika B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Amon, Angelika B. (Contributor)
Format: Article
Language:English
Published: Landes Bioscience, 2011-09-15T16:15:31Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items