CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma

We report the application of quantitative mass spectrometry to identify plasma membrane proteins differentially expressed in melanoma cells with high vs. low metastatic abilities. Using stable isotope labeling with amino acids in culture (SILAC) coupled with nanospray tandem mass spectrometry, we id...

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Main Authors: Liu, Hui (Contributor), Ong, Shao-En (Contributor), Badu-Nkansah, Kwabena (Contributor), Schindler, Jeffrey W. (Contributor), White, Forest M. (Contributor), Hynes, Richard O (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hynes, Richard O. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2011-10-24T19:46:49Z.
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