DNA repair modulates the vulnerability of the developing brain to alkylating agents

DNA repair modulates the vulnerability of the developing brain to alkylating agents

Neurons of the developing brain are especially vulnerable to environmental agents that damage DNA (i.e., genotoxicants), but the mechanism is poorly understood. The focus of the present study is to demonstrate that DNA damage plays a key role in disrupting neurodevelopment. To examine this hypothesi...

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Bibliographic Details
Main Authors: Samson, Leona D. (Contributor), Kisby, Glen E. (Author), Olivas, A. (Author), Park, T. (Author), Churchwell, Mona (Author), Doerge, Daniel R. (Author), Gerson, S. L. (Author), Turker, M. S. (Author)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor)
Format: Article
Language:English
Published: Elsevier Pub. Co., 2011-11-02T16:56:47Z.
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