Free-Flow Zone Electrophoresis of Peptides and Proteins in PDMS Microchip for Narrow pI Range Sample Prefractionation Coupled with Mass Spectrometry

Free-Flow Zone Electrophoresis of Peptides and Proteins in PDMS Microchip for Narrow pI Range Sample Prefractionation Coupled with Mass Spectrometry

In this paper, we are evaluating the strategy of sorting peptides/proteins based on the charge to mass without resorting to ampholytes and/or isoelectric focusing, using a single- and two-step free-flow zone electrophoresis. We developed a simple fabrication method to create a salt bridge for free-f...

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Bibliographic Details
Main Authors: Chan, Michael (Author), Song, Yong-Ak (Contributor), Celio, Chris (Contributor), Tannenbaum, Steven Robert (Contributor), Wishnok, John S. (Contributor), Han, Jongyoon (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Tannenbaum, Steven R. (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2011-11-02T19:47:12Z.
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