PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density

PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density

PSD-95, a membrane-associated guanylate kinase, is the major scaffolding protein in the excitatory postsynaptic density (PSD) and a potent regulator of synaptic strength. Here we show that PSD-95 is in an extended configuration and positioned into regular arrays of vertical filaments that contact bo...

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Bibliographic Details
Main Authors: Chen, Xiaobing (Author), Nelson, Christopher D. (Contributor), Li, Xiang (Author), Winters, Christine A. (Author), Azzam, Rita (Author), Sousa, Alioscka A. (Author), Leapman, Richard D. (Author), Gainer, Harold (Author), Sheng, Morgan Hwa-Tze (Contributor), Reese, Thomas S. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2011-11-09T16:01:08Z.
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