An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells

Glioblastoma (GBM, WHO grade IV) is an aggressively proliferative and invasive brain tumor that carries a poor clinical prognosis with a median survival of 9 to 12 months. In a prior phosphoproteomic study performed in the U87MG glioblastoma cell line, we identified tyrosine phosphorylation events t...

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Main Authors: Naegle, Kristen Marie (Contributor), Huang, Paul H. (Contributor), White, Forest M. (Contributor), Joughin, Brian Alan (Author), Yaffe, Michael B (Author), Lauffenburger, Douglas A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Lauffenburger, Douglas A. (Contributor), Joughin, Brian A. (Contributor), Yaffe, Michael B. (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2011-11-16T19:46:36Z.
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