Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic alpha-Bromoketones
The first asymmetric Kumada reactions of alkyl electrophiles are described, specifically, cross-couplings of racemic α-bromoketones with aryl Grignard reagents. Several features of this investigation are of interest. First, the couplings proceed at remarkably low temperature (−40 or −60 °C), which e...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society,
2011-12-14T21:48:47Z.
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| Subjects: | |
| Online Access: | Get fulltext |