A research-inspired laboratory sequence investigating acquired drug resistance

Here, we present a six-session laboratory exercise designed to introduce students to standard biochemical techniques in the context of investigating a high impact research topic, acquired resistance to the cancer drug Gleevec. Students express a Gleevec-resistant mutant of the Abelson tyrosine kinas...

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Bibliographic Details
Main Authors: Taylor, Elizabeth Vogel (Contributor), Fortune, Jennifer A. (Contributor), Drennan, Catherine L (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Drennan, Catherine L. (Contributor)
Format: Article
Language:English
Published: John Wiley & Sons, 2011-12-19T20:54:12Z.
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