Signaling network state predicts Twist-mediated effects on breast cell migration across diverse growth factor contexts

Signaling network state predicts Twist-mediated effects on breast cell migration across diverse growth factor contexts

Epithelial-mesenchymal transition (EMT), whether in developmental morphogenesis or malignant transformation, prominently involves modified cell motility behavior. Although major advances have transpired in understanding the molecular pathways regulating the process of EMT induction per se by certain...

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Main Authors: Kim, Hyung-Do (Contributor), Meyer, Aaron Samuel (Contributor), Wagner, Joel Patrick (Contributor), Wells, Alan (Author), Gertler, Frank (Contributor), Hughes-Alford, Shannon Kay (Author), Lauffenburger, Douglas A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Lauffenburger, Douglas A. (Contributor), Alford, Shannon K. (Contributor)
Format: Article
Language:English
Published: American Society of Biochemistry and Molecular Biology, 2012-01-04T19:53:42Z.
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