Eukaryotic Cells Producing Ribosomes Deficient in Rpl1 Are Hypersensitive to Defects in the Ubiquitin-Proteasome System

It has recently become clear that the misassembly of ribosomes in eukaryotic cells can have deleterious effects that go far beyond a simple shortage of ribosomes. In this work we find that cells deficient in ribosomal protein L1 (Rpl1; Rpl10a in mammals) produce ribosomes lacking Rpl1 that are expor...

Full description

Bibliographic Details
Main Authors: McIntosh, Kerri B. (Author), Bhattacharya, Arpita (Contributor), Willis, Ian M. (Author), Warner, Jonathan R. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-08T17:07:19Z.
Subjects:
Online Access:Get fulltext