Designer Lipid-Like Peptides: A Class of Detergents for Studying Functional Olfactory Receptors Using Commercial Cell-Free Systems

Designer Lipid-Like Peptides: A Class of Detergents for Studying Functional Olfactory Receptors Using Commercial Cell-Free Systems

A crucial bottleneck in membrane protein studies, particularly G-protein coupled receptors, is the notorious difficulty of finding an optimal detergent that can solubilize them and maintain their stability and function. Here we report rapid production of 12 unique mammalian olfactory receptors using...

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Bibliographic Details
Main Authors: Baaske, Philipp (Author), Wienken, Christoph J. (Author), Jerabek-Willemsen, Moran (Author), Duhr, Stefan (Author), Luo, Yuan (Author), Braun, Dieter (Author), Corin, Karolina A. (Contributor), Ravel, Deepali B. (Contributor), Song, Junyao (Contributor), Brown, Emily E. (Contributor), Wang, Xiaoqiang (Contributor), Zhang, Shuguang (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-08T18:41:37Z.
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