A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

Insulin signaling has a profound effect on longevity and the oxidative stress resistance of animals. Inhibition of insulin signaling results in the activation of DAF-16/FOXO and SKN-1/Nrf transcription factors and increased animal fitness. By studying the biological functions of the endogenous RNA i...

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Main Authors: Mansisidor, Andres R. (Author), Cecere, Germano (Author), Hoersch, Sebastian (Contributor), Jensen, Morten B. (Author), Kawli, Trupti (Author), Kennedy, Lisa M. (Author), Chavez, Violeta (Author), Tan, Man-Wah (Author), Lieb, Jason D. (Author), Grishok, Alla (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-10T20:04:11Z.
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