Tension, Free Space, and Cell Damage in a Microfluidic Wound Healing Assay

Tension, Free Space, and Cell Damage in a Microfluidic Wound Healing Assay

We use a novel, microfluidics-based technique to deconstruct the classical wound healing scratch assay, decoupling the contribution of free space and cell damage on the migratory dynamics of an epithelial sheet. This method utilizes multiple laminar flows to selectively cleave cells enzymatically, a...

Full description

Bibliographic Details
Main Authors: Murrell, Michael (Contributor), Kamm, Roger Dale (Contributor), Matsudaira, Paul T. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-15T17:20:45Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items