Tension, Free Space, and Cell Damage in a Microfluidic Wound Healing Assay
We use a novel, microfluidics-based technique to deconstruct the classical wound healing scratch assay, decoupling the contribution of free space and cell damage on the migratory dynamics of an epithelial sheet. This method utilizes multiple laminar flows to selectively cleave cells enzymatically, a...
Main Authors: | Murrell, Michael (Contributor), Kamm, Roger Dale (Contributor), Matsudaira, Paul T. (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2012-02-15T17:20:45Z.
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Subjects: | |
Online Access: | Get fulltext |
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