A general screening strategy for peptide-based fluorogenic ligands
A systematic and general approach for identifying efficient probes for class I PDZ domains based on environment-sensitive chromophores is presented. A series of peptides derived from the C-terminal sequence of Stargazin was first used with PDZ domains of PSD-95 and Shank3 to identify the optimal pos...
| Main Authors: | , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society,
2012-03-26T14:54:31Z.
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| Subjects: | |
| Online Access: | Get fulltext |