A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex

A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex

Technologies for silencing the electrical activity of genetically targeted neurons in the brain are important for assessing the contribution of specific cell types and pathways toward behaviors and pathologies. Recently we found that archaerhodopsin-3 from Halorubrum sodomense (Arch), a light-driven...

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Main Authors: Han, Xue (Contributor), Chow, Brian Y. (Contributor), Zhou, Huihui (Contributor), Klapoetke, Nathan Cao (Contributor), Chuong, Amy S. (Contributor), Rajimehr, Reza (Contributor), Yang, Aimei (Contributor), Baratta, Michael V. (Contributor), Winkle, Jonathan Andrew (Contributor), Desimone, Robert (Contributor), Boyden, Edward Stuart (Contributor)
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor)
Format: Article
Language:English
Published: Frontiers Research Foundation, 2012-04-13T16:59:59Z.
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