Millisecond-Timescale Optical Control of Neural Dynamics in the Nonhuman Primate Brain

To understand how brain states and behaviors are generated by neural circuits, it would be useful to be able to perturb precisely the activity of specific cell types and pathways in the nonhuman primate nervous system. We used lentivirus to target the light-activated cation channel channelrhodopsin-...

Full description

Bibliographic Details
Main Authors: Han, Xue (Contributor), Qian, Xiaofeng (Contributor), Bernstein, Jacob G. (Contributor), Zhou, Huihui (Contributor), Talei Franzesi, Giovanni (Contributor), Stern, Patrick (Contributor), Bronson, Roderick T. (Contributor), Desimone, Robert (Contributor), Graybiel, Ann M (Author), Boyden, Edward (Author)
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Graybiel, Ann M. (Contributor), Boyden, Edward Stuart (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2012-04-18T15:13:38Z.
Subjects:
Online Access:Get fulltext