High-performance genetically targetable optical neural silencing by proton pumps

High-performance genetically targetable optical neural silencing by proton pumps

The ability to silence the activity of genetically specified neurons in a temporally precise fashion would provide the opportunity to investigate the causal role of specific cell classes in neural computations, behaviours and pathologies. Here we show that members of the class of light-driven outwar...

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Main Authors: Chow, Brian Y. (Contributor), Han, Xue (Contributor), Dobry, Allison S. (Contributor), Qian, Xiaofeng (Contributor), Chuong, Amy S. (Contributor), Li, Mingjie (Contributor), Henninger, Michael Alan (Contributor), Belfort, Gabriel M. (Contributor), Lin, Yingxi (Contributor), Monahan, Patrick Erin (Contributor), Boyden, Edward Stuart (Contributor)
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Nuclear Science and Engineering (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-04-19T14:28:32Z.
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