Genome-wide identification and characterization of replication origins by deep sequencing

Genome-wide identification and characterization of replication origins by deep sequencing

Background DNA replication initiates at distinct origins in eukaryotic genomes, but the genomic features that define these sites are not well understood. Results We have taken a combined experimental and bioinformatic approach to identify and characterize origins of replication in three distantly re...

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Bibliographic Details
Main Authors: Xu, Jia (Author), Yanagisawa, Yoshimi (Author), Tsankov, Alexander M (Author), Hart, Christopher (Author), Aoki, Keita (Author), Kommajosyula, Naveen (Author), Steinmann, Kathleen E. (Author), Bochicchio, James (Author), Russ, Carsten (Author), Regev, Aviv (Contributor), Rando, Oliver J (Author), Nusbaum, Chad (Author), Niki, Hironori (Author), Milos, Patrice M. (Author), Weng, Zhiping (Author), Rhind, Nicholas (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Springer (Biomed Central Ltd.), 2012-05-25T17:48:47Z.
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