Predicting transcription factor specificity with all-atom models
The binding of a transcription factor (TF) to a DNA operator site can initiate or repress the expression of a gene. Computational prediction of sites recognized by a TF has traditionally relied upon knowledge of several cognate sites, rather than an ab initio approach. Here, we examine the possibili...
Main Authors: | , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Oxford University Press (OUP),
2012-05-25T19:57:05Z.
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Subjects: | |
Online Access: | Get fulltext |