Predicting transcription factor specificity with all-atom models

The binding of a transcription factor (TF) to a DNA operator site can initiate or repress the expression of a gene. Computational prediction of sites recognized by a TF has traditionally relied upon knowledge of several cognate sites, rather than an ab initio approach. Here, we examine the possibili...

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Bibliographic Details
Main Authors: Virnau, Peter (Author), Rahi, Sahand Jamal (Contributor), Mirny, Leonid A. (Contributor), Kardar, Mehran (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2012-05-25T19:57:05Z.
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