Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

The molecular mechanisms that drive mucosal T helper type 2 (T[subscript H]2) responses against parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that TFF2 (trefoil factor 2), an epithelial cell-derived repair molecule, is needed for the control of lung injury c...

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Main Authors: Wills-Karp, Marsha (Author), Rani, Reena (Author), Dienger, Krista (Author), Lewkowich, Ian (Author), Fox, James G. (Contributor), Perkins, Charles (Author), Lewis, Lauren (Author), Finkelman, Fred D. (Author), Smith, Dirk E. (Author), Bryce, Paul J. (Author), Kurt-Jones, Evelyn A. (Author), Wang, Timothy C. (Author), Sivaprasad, Umasundari (Author), Hershey, Gurjit K. (Author), Herbert, De'Broski R. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, The, 2012-07-23T15:50:29Z.
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