ATP-Sensitive Potassium Channels Exhibit Variance in the Number of Open Channels below the Limit Predicted for Identical and Independent Gating
In small cells containing small numbers of ion channels, noise due to stochastic channel opening and closing can introduce a substantial level of variability into the cell's membrane potential. Negatively cooperative interactions that couple a channel's gating conformational change to the...
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Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2012-07-23T18:16:53Z.
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Online Access: | Get fulltext |