Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

Genome-scale engineering of living organisms requires precise and economical methods to efficiently modify many loci within chromosomes. One such example is the directed integration of chemically synthesized single-stranded deoxyribonucleic acid (oligonucleotides) into the chromosome of Escherichia...

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Main Authors: Carr, Peter A., Sr (Contributor), Wang, Harris H. (Author), Sterling, Bram Henry (Contributor), Isaacs, Farren J. (Author), Lajoie, Marc J. (Author), Xu, George Jing (Contributor), Church, George M. (Author), Jacobson, Joseph (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Center for Bits and Atoms (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2012-07-24T13:08:14Z.
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