Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates

A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.

Bibliographic Details
Main Authors: Dooleweerdt, Karin (Contributor), Fors, Brett P. (Contributor), Buchwald, Stephen Leffler (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Buchwald, Stephen L. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2012-07-31T13:39:58Z.
Subjects:
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