The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell that manipulate the immune response allowing it to establish a chronic infection. Crosses between the types I, II and III strains, which are prevalent in North America and Europe, have identified seve...

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Main Authors: Niedelman, Wendy Leah (Contributor), Rosowski, Emily Elizabeth (Contributor), Sprokholt, Joris Kasper (Contributor), Lim, Daniel Cham-Chin (Contributor), Arenas, Ailan Farid (Author), Melo, Mariane Bandeira (Contributor), Spooner, Eric (Contributor), Saeij, Jeroen (Contributor), Gold, Daniel A. (Author), Yaffe, Michael B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Yaffe, Michael B. (Contributor), Gold, Daniel (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-08-22T20:50:10Z.
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