SIRT2 Ablation Has No Effect on Tubulin Acetylation in Brain, Cholesterol Biosynthesis or the Progression of Huntington's Disease Phenotypes In Vivo
Huntington's disease (HD) is a devastating neurodegenerative disorder for which there are no disease-modifying treatments. The molecular pathogenesis of HD is complex and many mechanisms and cellular processes have been proposed as potential sites of therapeutic intervention. However, prior to...
Main Authors: | , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2012-08-29T12:43:14Z.
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Subjects: | |
Online Access: | Get fulltext |