Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

Mutations in the presenilin genes cause the majority of early-onset familial Alzheimer's disease. Recently, presenilin mutations have been identified in patients with dilated cardiomyopathy (DCM), a common cause of heart failure and the most prevalent diagnosis in cardiac transplantation patien...

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Main Authors: Li, A. (Author), Zhou, C. (Contributor), Moore, J. (Author), Zhang, P. (Author), Tsai, Tsung-Han (Contributor), Lee, Hsiang-Chieh (Contributor), Romano, D. M. (Author), McKee, M. L. (Author), Schoenfeld, D. A. (Author), Serra, M. J. (Author), Raygor, K. (Author), Cantiello, H. F. (Author), Fujimoto, James G. (Contributor), Tanzi, R. E. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Bentham Science Publishers, 2012-08-29T19:21:41Z.
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