Mammalian microRNAs predominantly act to decrease target mRNA levels
MicroRNAs (miRNAs) are endogenous ~22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translational efficiency and/or decreased mRNA levels, but the rel...
| Main Authors: | , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2012-08-29T20:43:55Z.
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| Subjects: | |
| Online Access: | Get fulltext |