Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
In cancer cells, genetic alterations can activate proto-oncogenes, thereby contributing to tumorigenesis. However, the protein products of oncogenes are sometimes overexpressed without alteration of the proto-oncogene. Helping to explain this phenomenon, we found that when compared to similarly prol...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier,
2012-08-30T15:13:08Z.
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| Subjects: | |
| Online Access: | Get fulltext |