Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
In cancer cells, genetic alterations can activate proto-oncogenes, thereby contributing to tumorigenesis. However, the protein products of oncogenes are sometimes overexpressed without alteration of the proto-oncogene. Helping to explain this phenomenon, we found that when compared to similarly prol...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2012-08-30T15:13:08Z.
|
Subjects: | |
Online Access: | Get fulltext |