Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction

For subunit vaccines, adjuvants play a key role in shaping immunological memory. Nanoparticle (NP) delivery systems for antigens and/or molecular danger signals are promising adjuvants capable of promoting both cellular and humoral immune responses, but in most cases the mechanisms of action of thes...

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Bibliographic Details
Main Authors: Moon, James J. (Contributor), Suh, Heikyung (Contributor), Li, Adrienne Victoria (Contributor), Ockenhouse, Christian F. (Author), Yadava, Anjali (Author), Irvine, Darrell J (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Irvine, Darrell J. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2012-09-04T14:42:04Z.
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