Combining metabolic and protein engineering of a terpenoid biosynthetic for overproduction and selectivity control

Combining metabolic and protein engineering of a terpenoid biosynthetic for overproduction and selectivity control

A common strategy of metabolic engineering is to increase the endogenous supply of precursor metabolites to improve pathway productivity. The ability to further enhance heterologous production of a desired compound may be limited by the inherent capacity of the imported pathway to accommodate high p...

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Bibliographic Details
Main Authors: Parayil Kumaran, Ajikumar (Contributor), Leonard, Effendi (Contributor), Prather, Kristala L. Jones (Contributor), Stephanopoulos, Gregory (Contributor), Xiao, Wen-Hai (Contributor), Tidor, Bruce (Contributor), Mo, Jeffrey David (Contributor), Thayer, Kelly Marie (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2012-09-25T12:32:32Z.
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