Combining metabolic and protein engineering of a terpenoid biosynthetic for overproduction and selectivity control
A common strategy of metabolic engineering is to increase the endogenous supply of precursor metabolites to improve pathway productivity. The ability to further enhance heterologous production of a desired compound may be limited by the inherent capacity of the imported pathway to accommodate high p...
Main Authors: | Parayil Kumaran, Ajikumar (Contributor), Leonard, Effendi (Contributor), Prather, Kristala L. Jones (Contributor), Stephanopoulos, Gregory (Contributor), Xiao, Wen-Hai (Contributor), Tidor, Bruce (Contributor), Mo, Jeffrey David (Contributor), Thayer, Kelly Marie (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences,
2012-09-25T12:32:32Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
by: Wang, Y., et al.
Published: (2013) -
Synthetic and biosynthetic studies on terpenoids
by: Akhila, A.
Published: (1980) -
The future of metabolic engineering and synthetic biology: Towards a systematic practice
by: Yadav, Vikramaditya G., et al.
Published: (2015) -
Molecular Characterization of Terpenoid Biosynthetic Genes and Terpenoid Accumulation in <i>Phlomis umbrosa</i> Turczaninow
by: Si-Yoon Hwang, et al.
Published: (2020-11-01) -
Engineering Yarrowia lipolytica for Campesterol Overproduction.
by: Hao-Xing Du, et al.
Published: (2016-01-01)