Enhancing Protease Activity Assay in Droplet-Based Microfluidics Using a Biomolecule Concentrator
We introduce an integrated microfluidic device consisting of a biomolecule concentrator and a microdroplet generator, which enhances the limited sensitivity of low-abundance enzyme assays by concentrating biomolecules before encapsulating them into droplet microreactors. We used this platform to det...
Main Authors: | Chen, Chia-Hung (Author), Sarkar, Aniruddh (Contributor), Song, Yong-Ak (Contributor), Miller, Miles Aaron (Contributor), Kim, Sung Jae (Contributor), Griffith, Linda G. (Contributor), Lauffenburger, Douglas A. (Contributor), Han, Jongyoon (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Goyal, Chia-Hung (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2012-09-25T14:05:25Z.
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Subjects: | |
Online Access: | Get fulltext |
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