Cu-Catalyzed Arylation of Phenols: Synthesis of Sterically Hindered and Heteroaryl Diaryl Ethers
Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl...
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society,
2012-09-28T15:20:06Z.
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| Subjects: | |
| Online Access: | Get fulltext |