Rational Approaches to Improving Selectivity in Drug Design
Appropriate tuning of binding selectivity is a primary objective in the discovery and optimization of a compound on the path toward developing a drug. The environment in which drugs act is complex, with many potential interaction partners. Proteins, DNA, RNA, lipids, sugars, metabolites, and other s...
Main Authors: | , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2012-10-02T15:15:23Z.
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Subjects: | |
Online Access: | Get fulltext |