Rational Approaches to Improving Selectivity in Drug Design
Appropriate tuning of binding selectivity is a primary objective in the discovery and optimization of a compound on the path toward developing a drug. The environment in which drugs act is complex, with many potential interaction partners. Proteins, DNA, RNA, lipids, sugars, metabolites, and other s...
| Main Authors: | , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2012-10-02T15:15:23Z.
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| Subjects: | |
| Online Access: | Get fulltext |