High-throughput in vivo vertebrate screening

We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and genetic screens on zebrafish larvae. The system automatically loads zebrafish from reservoirs or multiwell plates, and positions and rotates them for high-speed confocal imaging and laser manipulation of both supe...

Full description

Bibliographic Details
Main Authors: Pardo-Martin, Carlos (Contributor), Chang, Tsung-Yao (Contributor), Koo, Bryan Kyo (Contributor), Gilleland, Cody Lee (Contributor), Wasserman, Steven Charles (Contributor), Yanik, Mehmet Fatih (Contributor)
Other Authors: move to dc.description.sponsorship (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-10-04T16:15:36Z.
Subjects:
Online Access:Get fulltext