H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

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Abstract Background The histone variant H2A.Z has been implicated in nucleosome exchange, transcriptional activation and Polycomb repression. However, the relationships among these seemingly disparate functions remain obscure. Results We mapped H2A.Z genome-wide in mammalian ES cells and neural prog...

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Main Authors: Ku, Manching (Author), Rheinbay, Esther (Author), Endoh, Mitsuhiro (Author), Koseki, Haruhiko (Author), Koche, Richard Patrick (Contributor), Jaffe, Jacob D. (Author), Carr, Steven A. (Author), Bernstein, Bradley E. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2012-10-04T19:58:50Z.
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