Epigenetic memory in induced pluripotent stem cells

Epigenetic memory in induced pluripotent stem cells

Somatic cell nuclear transfer and transcription-factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues. Through different mechanisms and kinetics, these two reprogramming methods reset genomic methylation, an epigenetic mod...

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Main Authors: Kim, K. (Author), Doi, A. (Author), Wen, B. (Author), Ng, K. (Author), Zhao, R. (Author), Cahan, Patrick (Author), Kim, J. (Author), Aryee, M. J. (Author), Ji, H. (Author), Ehrlich, L. I. R. (Author), Yabuuchi, A. (Author), Takeuchi, A. (Author), Cunniff, K. C. (Author), Hongguang, H. (Author), Mckinney-Freeman, S. (Author), Naveiras, O. (Author), Yoon, T. J. (Author), Irizarry, Rafael A. (Author), Jung, N. (Author), Seita, J. (Author), Hanna, Jacob (Contributor), Murakami, P. (Author), Jaenisch, Rudolf (Contributor), Weissleder, R. (Author), Orkin, Stuart H. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-10-12T18:17:07Z.
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