Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells

Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells

Pyriplatin, cis-diammine(pyridine)chloroplatinum(II), a platinum-based antitumor drug candidate, is a cationic compound with anticancer properties in mice and is a substrate for organic cation transporters that facilitate oxaliplatin uptake. Unlike cisplatin and oxaliplatin, which form DNA cross-lin...

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Main Authors: Lovejoy, Katherine S. (Contributor), Lippard, Stephen J. (Contributor), Serova, Maria (Author), Bieche, Ivan (Author), Emami, Shahin (Author), D'Incalci, Maurizio (Author), Broggini, Massimo (Author), Erba, Eugenio (Author), Gespach, Christian (Author), Cvitkovic, Esteban (Author), Faivre, Sandrine (Author), Raymond, Eric (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2012-10-17T19:21:37Z.
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