Measuring chromosome conformation with degenerate labels

Although DNA conformation plays an integral role in all genetic processes from transcription to chromosome segregation, there is as yet no tractable method for capturing the in vivo conformation of a chromosome at high resolution. Labeling and fluorescently imaging thousands of loci along the chromo...

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Bibliographic Details
Main Authors: Ross, Brian Christopher (Contributor), Wiggins, Paul A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: American Physical Society, 2012-10-22T12:31:49Z.
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