Measuring chromosome conformation with degenerate labels
Although DNA conformation plays an integral role in all genetic processes from transcription to chromosome segregation, there is as yet no tractable method for capturing the in vivo conformation of a chromosome at high resolution. Labeling and fluorescently imaging thousands of loci along the chromo...
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Format: | Article |
Language: | English |
Published: |
American Physical Society,
2012-10-22T12:31:49Z.
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Online Access: | Get fulltext |