LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion

LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion

Successful execution of the meiotic program depends on the timely establishment and removal of sister chromatid cohesion. LAB-1 has been proposed to act in the latter by preventing the premature removal of the meiosis-specific cohesin REC-8 at metaphase I in C. elegans, yet the mechanism and scope o...

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Main Authors: Tzur, Yonatan B. (Author), Carvalho, Carlos Egydio de (Author), Nadarajan, Saravanapriah (Author), Van Bostelen, Ivo (Author), Gu, Yanjie (Author), Chu, Diana S. (Author), Colaiacovo, Monica P. (Author), Cheeseman, Iain M (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Cheeseman, Iain McPherson (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-10-30T16:47:43Z.
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