Tuning Genetic Clocks Employing DNA Binding Sites

Periodic oscillations play a key role in cell physiology from the cell cycle to circadian clocks. The interplay of positive and negative feedback loops among genes and proteins is ubiquitous in these networks. Often, delays in a negative feedback loop and/or degradation rates are a crucial mechanism...

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Bibliographic Details
Main Authors: Del Vecchio, Domitilla (Contributor), Jayanthi, Shridhar (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-11-14T16:03:54Z.
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