CA3 NMDA Receptors are Required for the Rapid Formation of a Salient Contextual Representation

CA3 NMDA Receptors are Required for the Rapid Formation of a Salient Contextual Representation

The acquisition of Pavlovian fear learning engages the hippocampus when the conditioned stimuli are multimodal or temporally isolated from the unconditioned stimuli. By subjecting CA3-NR1 KO mice to conditioning protocols that incorporate time-dependent components, we found that the loss of plastici...

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Bibliographic Details
Main Authors: McHugh, Thomas J. (Contributor), Tonegawa, Susumu (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), RIKEN-MIT Center for Neural Circuit Genetics (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2012-11-15T17:45:15Z.
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