Optogenetic stimulation of a hippocampal engram activates fear memory recall

Optogenetic stimulation of a hippocampal engram activates fear memory recall

A specific memory is thought to be encoded by a sparse population of neurons. These neurons can be tagged during learning for subsequent identification3 and manipulation. Moreover, their ablation or inactivation results in reduced memory expression, suggesting their necessity in mnemonic processes....

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Bibliographic Details
Main Authors: Liu, Xu (Contributor), Pang, Petti (Contributor), Puryear, Corey (Contributor), Govindarajan, Arvind (Contributor), Deisseroth, Karl (Author), Tonegawa, Susumu (Contributor), Ramirez Moreno, Steve (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), RIKEN-MIT Center for Neural Circuit Genetics (Contributor), Ramirez, Steve (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-11-15T18:26:52Z.
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