Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells

Under the instruction of cell-fate-determining, DNA-binding transcription factors, chromatin-modifying enzymes mediate and maintain cell states throughout development in multicellular organisms. Currently, small molecules modulating the activity of several classes of chromatin-modifying enzymes are...

Full description

Bibliographic Details
Main Authors: Kubicek, Stefan (Contributor), Gilbert, Joshua C. (Author), Fomina-Yadlin, Dina (Contributor), Gitlin, Alexander D. (Author), Yuan, Yuan (Contributor), Wagner, Florence F. (Author), Holson, Edward B. (Author), Luo, Tuoping (Author), Lewis, Timothy A. (Author), Taylor, Bradley (Author), Gupta, Supriya (Author), Shamji, Alykhan F. (Author), Wagner, Bridget K. (Author), Clemons, Paul A. (Author), Schreiber, Stuart L. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2012-11-15T20:17:26Z.
Subjects:
Article
Online Access:Get fulltext

Similar Items

Similar Items