Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase
Little is known about quality control of proteins that aberrantly or persistently engage the endoplasmic reticulum (ER)-localized translocon en route to membrane localization or the secretory pathway. Hrd1 and Doa10, the primary ubiquitin ligases that function in ER-associated degradation (ERAD) in...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Rockefeller University Press, The,
2012-11-16T20:11:38Z.
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| Subjects: | |
| Online Access: | Get fulltext |